A case of hemolytic anemia induced by application of .BETA.2 microglobulin adsorbent column to dialysis-related amyloidosis.
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چکیده
منابع مشابه
Reduction of circulating beta2-microglobulin level for the treatment of dialysis-related amyloidosis.
Dialysis-related amyloidosis (DRA) is a common complication associated with long-term haemodialysis therapy. The elimination of beta2-microglobulin (beta2m), the major constituent of the amyloid fibrils in DRA, from circulation has been expected to bring some clinical benefit. Recently, a direct haemoperfusion method using selective beta2m absorption column to eliminate circulating beta2m has b...
متن کاملbeta(2)-Microglobulin-selective direct hemoperfusion column for the treatment of dialysis-related amyloidosis.
Lixelle is a direct hemoperfusion-type adsorption column that was developed to selectively eliminate beta2-microglobulin (beta2-m) from the circulating blood of patients with dialysis-related amyloidosis (DRA). The adsorbent in Lixelle comprises porous cellulose beads to which hydrophobic hexadecyl alkyl chain is covalently bound. One milliliter of wet Lixelle beads eliminates more than 1 mg of...
متن کاملCollagen plays an active role in the aggregation of beta2-microglobulin under physiopathological conditions of dialysis-related amyloidosis.
Dialysis-related amyloidosis is characterized by the deposition of insoluble fibrils of beta(2)-microglobulin (beta(2)-m) in the musculoskeletal system. Atomic force microscopy inspection of ex vivo amyloid material reveals the presence of bundles of fibrils often associated to collagen fibrils. Aggregation experiments were undertaken in vitro with the aim of reproducing the physiopathological ...
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15 صفحه اولHemolytic Anemia as an Outcome of Occupational Exposure to Formalin: A Case Report
ABSTRACT Background: Occupational exposure studies indicate that formaldehyde exposure causes temporary and consistent effects on industrial workers exposed to formalin. Case: The case was a 36-year-old man who had developed intravascular hemolytic anemia caused by formalin after inhalation exposure. Formalin is a clear solution of 37% formaldehyde in water. The primary route of exposure to f...
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ژورنال
عنوان ژورنال: Nihon Toseki Igakkai Zasshi
سال: 2002
ISSN: 1883-082X,1340-3451
DOI: 10.4009/jsdt.35.191